Dexamethasone for Post Traumatic Headache

  • End date
    Feb 26, 2024
  • participants needed
  • sponsor
    Montefiore Medical Center
Updated on 26 March 2022


This is a randomized study of intravenous metoclopramide + intravenous dexamethasone versus intravenous metoclopramide for patients with acute post-traumatic headache.

Condition Post-Traumatic Headache
Treatment Dexamethasone, Metoclopramide 10mg
Clinical Study IdentifierNCT04799015
SponsorMontefiore Medical Center
Last Modified on26 March 2022


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Inclusion Criteria

Included patients will be adults who meet International Classification of Headache Disorders criteria for acute post-traumatic headache. These are as follows
Traumatic injury to the head has occurred
Headache has developed within 7 days of injury to the head
Headache is not better accounted for by another diagnosis (eg, migraine or tension-type headache)
The headache must be rated as moderate or severe in intensity at the time of initial evaluation

Exclusion Criteria

Patients will be excluded if more than ten days have elapsed since the head trauma, if the headache has already been treated with an anti-dopaminergic medication, or for medication allergies or contra-indications including pheochromocytoma, seizure disorder, Parkinson's disease, use of MAO inhibitors, and use of anti-rejection transplant medications
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