Marijuana Use Strength Training and Alcohol Consumption (MUSTAC) Study

  • End date
    Mar 20, 2023
  • participants needed
  • sponsor
    University of Florida
Updated on 20 March 2021


Self-medication of pain by consuming alcohol and marijuana is common. However, the research regarding pain as a determinant for alcohol and marijuana use has relied on laboratory pain induction paradigms with limited clinical relevance. The study will assess demand for alcohol and marijuana before and after delayed onset muscle soreness (DOMS) induction in co-users. This will provide a clinically relevant, but time-limited, model for the effects of musculoskeletal pain on demand.

Condition Pain, Post-Surgical Pain, Pain (Pediatric), Pain, Chronic Pain, Chronic Pain, Post-Surgical Pain, Pain (Pediatric), chronic pains
Treatment Eccentric Biceps Flexion, Concentric Biceps Flexion
Clinical Study IdentifierNCT04791917
SponsorUniversity of Florida
Last Modified on20 March 2021


Yes No Not Sure

Inclusion Criteria

Age 21 years
Self-identify as White/Caucasian or Black/African American
Own a smartphone with cellular/data plan
Regularly co-use alcohol and smoked marijuana as indicated by scores of 3 on item 1 of the CUDIT-R and AUDIT
Willing and able to give informed consent

Exclusion Criteria

Participation in biceps-specific conditioning program in the past 6 months
Self-reported wrist/hand, elbow, or shoulder pain the past 3 months
Chronic medical condition that may affect pain perception (e.g. diabetes, fibromyalgia, headaches)
Self-reported kidney dysfunction, muscle damage, or major psychiatric disorder
Medical marijuana prescription
Consumption of marijuana using only non-inhalational methods (e.g. edibles, tinctures, or cannabidiol oil)
Score of 10 on Patient Health Questionnaire-9 (moderate depression)
Women who are pregnant, trying to become pregnant, or breastfeeding
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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