Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid

  • End date
    Mar 26, 2023
  • participants needed
  • sponsor
    NYU Langone Health
Updated on 26 March 2022


This is a split-scar study with a target sample size of 20. There are two interventions: fractional erbium:YAG-assisted drug delivery of 5-fluorouracil and fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide. Patients will undergo treatments in a series of 4 treatments at approximately 4 week ± 1 week intervals. Investigators will monitor for safety and continued benefit after the end of the interventional treatment.

Condition Keloid Scar
Treatment Fractional erbium:YAG-assisted drug delivery of 5-fluorouracil, Fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide
Clinical Study IdentifierNCT04786210
SponsorNYU Langone Health
Last Modified on26 March 2022


Yes No Not Sure

Inclusion Criteria

Age 18-89
Has one large keloid scar or at least two similar but separate keloid scars
Keloid present for at least 1 year

Exclusion Criteria

Currently pregnant
Currently breastfeeding
Have taken oral retinoids within 6 months of study initiation
Has had keloid treatment within 1 month of study initiation
Has active infection at treatment site
Has active malignancy
Presence of pedunculated keloid(s) or keloid(s) that are judged to be best treated with surgical excision first
Hypertrophic scars
Known hypersensitivity to TAC or 5-FU
Chronic systemic corticosteroid or immunosuppressive medication use
Has intolerance to anesthesia
Has known connective tissue disease
Has known infectious disease
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact



Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note