Inhaled Budesonide in Transient Tachypnea of the Newborn

  • participants needed
  • sponsor
    Makassed General Hospital
Updated on 15 October 2021


Background: Transient tachypnea of the newborn (TTN) caused by lung edema resulting from delayed absorption of fetal alveolar lung fluid and is a common cause of admission of late preterm and full-term infants to neonatal intensive care units. Infant born by C-section and those with perinatal asphyxia, umbilical cord prolapse or certain maternal condition (asthma, diabetes, or analgesia) are more prone to develop TTN. Conventional treatment involves appropriate oxygen administration and continuous positive airway pressure in some cases. Hastening the clearance of lung liquid should shorten the duration of the symptoms and reduce complications.

Objectives: This study aims to determine the effectiveness of inhaled budesonide in the treatment of this disorder through determining whether it reduces the duration of oxygen therapy and respiratory symptoms and shortens hospital stay in term infants with transient tachypnea of the newborn

Condition respiratory distress
Treatment Placebo, Inhaled corticosteroids
Clinical Study IdentifierNCT04758078
SponsorMakassed General Hospital
Last Modified on15 October 2021

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