The Clinical Impact of L-PRF H-PRF or the Use of Surgical Stent on Palatal Donor Site Healing.

  • STATUS
    Recruiting
  • End date
    Feb 28, 2023
  • participants needed
    30
  • sponsor
    Abdo Y Ismail
Updated on 11 March 2021

Summary

A Randomized, Three Parallel Arms Clinical Trial to evaluate s the clinical impact of L-PRF vs H-PRF vs Palatal stent on the healing of the donor palatal site.

Description

A Randomized, Three Parallel Arms Clinical Trial. The primary objective is to assess the clinical impact of L-PRF vs H-PRF vs Palatal stent on the healing of the donor palatal site by comparing the percentage of re-epithelization of the palatal donor site at 5, 10, 14 and 21 days using a standardized intraoral palatal photo.

The secondary objective is to compare the post op discomfort between the three groups during the healing period daily for 2 weeks using the Visual Analogue Scale (VAS) and Analgesic consumption.

All subjects from the University of Kentucky College of Dentistry clinics. Subjects that are coming increasing the width of keratinized tissue or for the treatment of gingival recession, and match the inclusion criteria will be told about the research and offered the opportunity to participate.

Details
Condition Lack of Keratinized Gingiva
Treatment L-PRF (Leucocyte- platelet rich fibrin), H-PRF (Horizontal -platelet rich fibrin), Surgical stent
Clinical Study IdentifierNCT04758702
SponsorAbdo Y Ismail
Last Modified on11 March 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Subjects between 18-65 years of age
Subjects need FGG or de-epithelialized Connective tissue graft
Good oral hygiene (Plaque and bleeding indexes <20%)
Subjects can withstand alginate impression or wear a retainer
No other surgery or need for analgesics at the same site

Exclusion Criteria

Subjects with any systemic disorders that might compromise wound healing (Uncontrolled diabetes mellitus, rheumatoid arthritis, osteoporosis, chemotherapy/radiotherapy and immunological disorders)
Smokers
Patients not maintaining oral hygiene (plaque score >20%)
Pregnant or breastfeeding females
Inability to provide informed consent
Grafts thickness more than 2mm will be excluded from the study
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