This study is a single-site, double-blinded, randomized clinical trial designed to elucidate
mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)
Patients treating twice daily using a non-invasive brainstem modulation device. Study
participants will self-administer treatments in the home setting over a period of 12 weeks.
Changes in cerebral blood flow perfusion, cerebrovascular reactivity and functional
connectivity between the pre-treatment baseline and the end of the treatment period will be
monitored and compared to changes in validated standardized clinical measures of motor and
non-motor symptoms in PD.
If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
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