Comparison of the Nociception Monitoring Devices During Cardiac Surgery. (SYDNOS)

  • End date
    Sep 1, 2023
  • participants needed
  • sponsor
    Kuopio University Hospital
Updated on 16 September 2022


The purpose of this study is to compare the values of Surgical Pleth Index (SPI) and Nociception Level Index (NOL) measured simultaneously during cardiac surgery.


Participants are given oral and written information about the course of the trial, associated risks and benefits and about the handling of the personal data on the day before the surgery by one of the investigators. Participants are also given written information about patient's rights and insurance, the aim of the trial and its course. 40 adult cardiac surgery patients will be recruited for the study. NOL and SPI values will be measured during the cardiac surgery procedure. All patients receive oral premedication and standardized anesthesia.

Condition Cardiac Surgery
Treatment PMD-200 monitor, Surgical Pleth Index monitor
Clinical Study IdentifierNCT04712773
SponsorKuopio University Hospital
Last Modified on16 September 2022


Yes No Not Sure

Inclusion Criteria

coronary artery disease of heart valve disorder qualified for the surgical treatment
participant understands the course of the trial and its aim
participant has given informed written consent

Exclusion Criteria

participant has not given consent
neurological or psychical disorders (psychiatric medication)
alcohol or substance abuse
central nervous system medication (medication for epilepsy or neuropathic pain)
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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