Cyclophotocoagulation in Glaucoma

  • End date
    Aug 4, 2023
  • participants needed
  • sponsor
    CHU de Quebec-Universite Laval
Updated on 4 March 2021


Transscleral cyclophotocoagulation of the ciliary body is an effective technique to reduce intraocular pressure in case of glaucoma. Due to concerns over complications, the main indications for this second-line treatment are refractory glaucoma medication / surgery and low visual prognosis. The 2000 milliwatts (mW) for 2 seconds settings are used by the majority of researchers and clinicians according to the published literature. Some have proposed using 1250 mW for 4 seconds to improve the use of this medical procedure.

The aim of this study is to determine how different parameters affect the efficacy of the treatment. This is a prospective double-blinded randomized controlled trial comparing two groups, the experimental group using 1250 mW for 4 seconds and the control group using 2000 mW for 2 seconds.

Condition Ocular Hypertension, Ocular Hypertension, Glaucoma, Glaucoma
Treatment Cyclophotocoagulation protocol, Conventional cyclophotocoagulation, Modified cyclophotocoagulation
Clinical Study IdentifierNCT02875158
SponsorCHU de Quebec-Universite Laval
Last Modified on4 March 2021


Yes No Not Sure

Inclusion Criteria

Patients with poorly controlled high pressure glaucoma
Cyclophotocoagulation necessary to prevent visual loss
Cyclophotocoagulation necessary to prevent or to reduce ocular discomfort

Exclusion Criteria

Patient has already undergone a cyclophotocoagulation or cryotherapy treatment in the same eye for glaucoma
Patients receiving concomitant treatment the same day as the intervention
Patient not able to follow the prescribed post-operative treatment
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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