The COVID-RASi study is an international randomized clinical trial that will evaluate the potential benefit of angiotensin modulators on clinical outcomes, in COVID-19 patients who are at high-risk for cardiovascular disease. The purpose of this study is to determine if renin-angiotensin system inhibitors (RASi), with angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB), has a beneficial effect in high-risk older patients with COVID-19 infections, by reducing ICU admission, ventilator requirement or death. We would also like to determine if there are differences between ACEi and ARB therapeutic treatments.
Condition | cardiovascular disorders, cardiovascular disease (cvd), *COVID-19, Covid-19, cardiovascular system diseases, Cardiovascular Disease, cardiovascular diseases |
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Treatment | Angiotensin converting enzyme inhibitor, Angiotensin II Receptor Blockers, Angiotensin II Receptor Blockers |
Clinical Study Identifier | NCT04591210 |
Sponsor | Ottawa Heart Institute Research Corporation |
Last Modified on | 26 June 2021 |
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