The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction

  • STATUS
    Recruiting
  • End date
    Jul 25, 2027
  • participants needed
    88
  • sponsor
    Istituto Ortopedico Rizzoli
Updated on 15 May 2022

Summary

The aim of the study is the evaluation of both clinical and radiological results in patients undergone to cruciate ligament reconstruction with concomitant cartilaginous lesion treated with or without nanofractures.

Description

The anterior cruciate ligament lesion is one of the most common disease conditions in the orthopedic clinical practice. The mechanism of injury is due to a direct or indirect knee trauma causing both ligamentous breaking and surface articular stress, with cartilaginous lesion often associated to the lesion of the anterior cruciate ligament.

The treatment of these lesions in combination with the treatment of the anterior cruciate ligament is controversial, more controversial is to understand the indication to treatment for these lesions.

In order to clarify this aspect and provide a more reliable therapeutic indication for the treatment of the cartilaginous lesion with concomitant anterior cruciate ligament lesion we want to compare the clinical outcomes of the non-treated cartilaginous lesions against the treated cartilaginous lesions wiht nonofractures.

Details
Condition Cruciate Ligament Rupture, Cartilage Injury
Treatment Nanofractures, no treatment cartilaginous lesions
Clinical Study IdentifierNCT04184687
SponsorIstituto Ortopedico Rizzoli
Last Modified on15 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Male or female patients, 18 < age < 55
Patients with complete ACL injury candidates for surgical reconstruction of the same
Cartilaginous lesion of the femur-tibial compartment of grade III-IV ICRS ≤3 cm2 confirmed intra-operatively
Patients without evidence of osteoarthritis
Patients' ability and consent to participate in clinical and radiological follow-up
Signature of informed consent

Exclusion Criteria

Patients incapable of understanding and of wanting
State of immunodepression
Patients with malignant neoplasms
Patients suffering from rheumatic diseases
Patients suffering from non-compensated diabetes
Patients suffering from uncompensated thyroid metabolic disorders
Patients abusing alcoholic beverages, drugs or drugs
Patients with axial deviations> 5 °
Body Mass Index> 35
Patients treated with surgery at the same knee in the previous 12 months
Cartilaginous lesions grade I-II according to the ICRS score
Cartilage lesions with a diameter greater than 3 cm²
Non-suturable meniscal lesions requiring meniscectomy> 50% and patients with previous meniscectomies> 50% in the same compartment
Need for further associated surgical procedures in addition to the reconstruction of ACL and possibly the nanofractures
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