Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss

  • End date
    Jan 1, 2022
  • participants needed
  • sponsor
    Meir Medical Center
Updated on 1 March 2021


Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation


This randomized control trial will investigate whether local tranexamic acid is efficient for decreasing bleeding during vaginal hysterectomy.

The investigators will randomize local placebo (saline) vs. local 1 gr tranexamic acid; IV 1gr diluted in 100 ml saline and IV 100 ml saline at the beginning of surgery.

Condition Hemorrhage
Treatment local tranexamic acid injection, local normal saline injection to cervix, IV 1 g tranexamic acid, IV 1 g normal saline
Clinical Study IdentifierNCT04760301
SponsorMeir Medical Center
Last Modified on1 March 2021


Yes No Not Sure

Inclusion Criteria

-90 years old female patients going through vaginal hysterctomy

Exclusion Criteria

massive bleeding during operation due to major vessles injury
known coagulopathies
sensitivity to tranexamic acid
medical need in tranexamic acid administration during operation due to bleeding
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