Semitendinosus Graft as Meniscal Transplant

  • STATUS
    Recruiting
  • End date
    Jan 1, 2026
  • participants needed
    10
  • sponsor
    Karolinska Institutet
Updated on 11 July 2022

Summary

Removal of meniscal tissue is described to result in poor knee function and a significant risk for future development of osteoarthritis. Different implants have been suggested to substitute a removed meniscus. Meniscal allograft transplantation is not widely available due to costs and availability. The semitendinosus tendon is a known graft with biological properties with potential to remodel and revascularize in an intraarticular environment such as anterior cruciate ligament reconstruction. The objective for this study was to investigate whether the semitendinosus tendon graft could function as a meniscal transplant.

Details
Condition Patient Satisfaction, Graft Failure, Osteo Arthritis Knee, ACL, Meniscus Tear
Treatment Surgical technique
Clinical Study IdentifierNCT04753424
SponsorKarolinska Institutet
Last Modified on11 July 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Previous subtotal or total meniscectomy
Post meniscectomy symptoms
No osteoarthritic changes on radiography more than Ahlbäck 1
Knee aligment (hip-knee-angle) +/- 3°
No persisting ACL insufficiency

Exclusion Criteria

Difficulty understanding the instructions
Current psychiatric diagnosis
Smoking
Clear my responses

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