Buscopan in Patients Undergoing IVF/Intracytoplasmic Sperm Injection Treatment

  • End date
    Apr 30, 2024
  • participants needed
  • sponsor
    Chinese University of Hong Kong
Updated on 17 February 2021


To determine if the use of Buscopan in patients undergoing IVF/ICSI treatment with high uterine contraction frequency prior to embryo transfer has a higher live birth rate.

Condition assisted reproductive technology, Intracytoplasmic sperm injection, In Vitro Fertilization, In Vitro Fertilization, assisted reproductive technologies, icsi
Treatment Buscopan 20 milligrams/ML Injectable Solution
Clinical Study IdentifierNCT04751084
SponsorChinese University of Hong Kong
Last Modified on17 February 2021


Yes No Not Sure

Inclusion Criteria

Women undergoing embryo transfer in either fresh or frozen cycles

Exclusion Criteria

\- Women aged > 42 years old
Women with factors which will affect uterine contractility
congenital uterine anomaly
acquired uterine pathology such as myoma >5cm, adenomyosis >5cm or endometrial polyp
Women with presence of hydrosalpinx
Women undergoing pre-implantation genetic test in IVF cycles
History of allergy to misoprostol , Buscopan or same group of drug
Contraindication to the use of Buscopan e.g. glaucoma, myasthenia gravis, tachycardia, megacolon
Women who are on other smooth muscle relaxant other than Buscopan
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