A Study to Detect Progression of Mass Effect From Unilateral Brain Lesions

  • End date
    May 1, 2022
  • participants needed
  • sponsor
    Mayo Clinic
Updated on 14 February 2021


The purpose of this research is to gather information on the safety and effectiveness of the Brain4Care device for measuring intracranial pressure without invasive procedures.

Condition Non-traumatic Hemispheric Brain Lesions, Non-traumatic Hemispheric Brain Lesions
Treatment Non-invasive bilateral monitoring of ICP waveform
Clinical Study IdentifierNCT04745884
SponsorMayo Clinic
Last Modified on14 February 2021


Yes No Not Sure

Inclusion Criteria

Adult patients with non-traumatic hemispheric brain lesions deemed at risk for progression of mass effect and possible subfalcine and/or uncal herniation
Patients admitted the Neuroscience ICU for serial neurological monitoring
Patients whose care is not expected to include immediate surgical decompression

Exclusion Criteria

Patients under the age of 18
Patients who are unable to provide consent due to neurologic deficit and does not have a surrogate decision maker available to provide consent
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