Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum
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- STATUS
- Recruiting
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- End date
- Oct 16, 2023
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- participants needed
- 80
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- sponsor
- Poitiers University Hospital
Summary
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Clinical studies have demonstrated a link between staphylococcal skin colonization and the pathogenesis of AD, but the implication of bacterial virulence factors remains largely uncharacterized. Finally, AD is often associated with herpes simplex skin infections. The aim of this project is to investigate the role of staphylococcal toxins in the exacerbation and maintenance of atopic skin inflammation and in the occurrence of infectious complications such as eczema herpeticum.
Details
| Condition | bacterial toxin, Eczema, Eczema (Atopic Dermatitis - Pediatric), Staphylococcus aureus, cytokine, ATOPIC DERMATITIS, Eczema (Atopic Dermatitis), ATOPIC DERMATITIS, Dermatitis, Atopic, Dermatite Atopique, Eczéma (Dermatite Atopique), Dermatitis, Hand Dermatitis, Eczema (Atopic Dermatitis), Dermatitis, Atopic, Hand Dermatitis, Eczema (Atopic Dermatitis - Pediatric), Immune Response, Eczéma (Dermatite Atopique), Dermatite Atopique, s. aureus, cytokines, T Cells Subsets |
|---|---|
| Treatment | Skin biopsies and blood samples |
| Clinical Study Identifier | NCT04274348 |
| Sponsor | Poitiers University Hospital |
| Last Modified on | 5 February 2021 |
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