Sleep IntervEntion as Symptom Treatment for ADHD

  • End date
    Dec 4, 2024
  • participants needed
  • sponsor
    Universitaire Ziekenhuizen Leuven
Updated on 4 April 2021


Up to 72% of adolescents with ADHD portray sleep problems. The most common sleep difficulties in adolescents with ADHD are initial insomnia, nocturnal awakenings, non-restorative or restless sleep. These difficulties seem to be causally related to increased ADHD symptom impairment, oppositional and depressive symptomatology, and functional impairments in daily life, resulting in a vicious circle of sleep problems and impairment. Thus, reducing sleep problems is an important intervention target. However, to date there is no evidence-based cognitive behavioral sleep treatment available. Sleep-focused treatments need adaptation towards this developmental phase/disorder for effectiveness, as ADHD and sleep problems are bi-directional. Therefore, a blended treatment targeting the core deficits integrating motivational interviewing, planning skills and sleep interventions is needed. Thus, the aim of this project is testing the short and 3 months follow-up effectiveness of the blended CBT sleep intervention in adolescents with ADHD.

Condition Cognitive Therapy, Attention deficit hyperactivity disorder, Attention Deficit/Hyperactivity Disorder (ADHD - Pediatric), Attention Deficit/Hyperactivity Disorder (ADHD - Adults), Family Medicine-ADHD Pediatrics, Adolescence, Sleep, Attention Deficit/Hyperactivity Disorder (ADHD - Adults), Attention Deficit/Hyperactivity Disorder (ADHD - Pediatric), Family Medicine-ADHD Pediatrics, adhd, cognitive behavioral therapy, cognitive behavior therapy, cognitive behavioural therapy, cognitive behaviour therapy
Treatment Treatment as usual for ADHD, SIESTA
Clinical Study IdentifierNCT04723719
SponsorUniversitaire Ziekenhuizen Leuven
Last Modified on4 April 2021


Yes No Not Sure

Inclusion Criteria

Attending secondary education and between 13-17 years old
prior diagnosis of ADHD (any presentation) and confirmation of DSM-5 criteria of ADHD in current study
Displaying sleep problems for at least 3 nights per week for at least 3 months
sleep onset latency of at least 20-30 minutes
and/or wake after sleep onset greater than 30 min
and/or an average sleep time of less than 7 hours
and at least one poor sleep hygiene practice
and experienced distress as indicated by parent/guardian and/or adolescent
estimated IQ80
stable ADHD medication use at least 4 weeks before start of treatment and no dose or medication type changes planned during active treatment

Exclusion Criteria

the following comorbidities: sleep-breathing disorder, restless leg syndrome, narcolepsy, conduct disorder, depressive disorder with suicide risk or active suicidality, autism spectrum disorder, or substance use disorder, with an exception for nicotine
acute crisis situation at home
physical problems that interfere with sleep (e.g. pain) or medical disorders and related medication that could affect sleep
participation in a behaviorally based sleep intervention in the 6 months prior to our study
currently taking pharmacological medication for sleep (including melatonin), anxiety or depression. Participation will be allowed after a two-week wash-out period of the medication
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact



Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note