Understanding the Microbiome-gut-brain axis in Alzheimer disease and its Role in Cognitive Decline

  • End date
    Jan 21, 2023
Updated on 14 June 2022
neurodegenerative disorders
Accepts healthy volunteers


The purpose of the study is looking at imbalances of the gut microbiome and how it relates to progression of neurodegenerative disorders like Alzheimer's and Dementia.


Study activities include visiting the Clinical Research Center at UMass Memorial Medical Center once every three months for a span of two years. Parking will be validated. Participants will be interviewed for an hour time period. Participants' blood will be drawn and an oral swab will be collected. Participants will also provide a stool sample that will be collected from home and sent in the mail. Participants will not need to change anything about their daily routine, diet, or medication.

Condition Dementia, Dementia, Alzheimer's Disease, Alzheimer's Disease, *Healthy Volunteers, Study visits every 3 months
Clinical Study IdentifierTX264379
Last Modified on14 June 2022


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What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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