Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19

  • STATUS
    Recruiting
  • End date
    Jul 27, 2022
  • participants needed
    100
  • sponsor
    University Hospital, Toulouse
Updated on 27 January 2021

Summary

For the last years, studies have described the " Post-intensive care Syndrome " (PICS), which consists in alteration of quality of life, cognition, autonomy and psychological disorders within the months after intensive-care. Patients with COVID-19 in intensive care units are at high risks to develop PICS.

The primary objective is to analyse the incidence of the post-traumatic stress disorder at 12 months after intensive-care for a COVID-19 Acute Respiratory Distress Syndrome (ARDS).

Description

Many studies have showed that ARDS survivors keep, even a long time after hospitalization, a functional respiratory disability, resulting on one hand from impaired diffusion of carbon monoxide, and on the other hand from a muscular weakness. Indeed, 67% of patients ventilated more than 10 days have a neuromyopathy whose recovery is uncertain.

Beside this, Long-term quality of life is worse than in general population, due in particular to depressive and anxiety disorders such as post-traumatic syndrome disorder with a prevalence around 22% after one year.

The follow-up will consist in phone call with an intensive care doctor. These visits would be the opportunity to screen the complications after intensive-care with, find solutions to cure them or decrease their impact on patient's life to improve quality of life and prevent the post-traumatic syndrome disorder PTSD. A review would be sent to the patients' General Practitioners at the end of each visit.

Details
Condition Coronavirus Infection, Pulmonary Disease, ADULT RESPIRATORY DISTRESS SYNDROME, Coronavirus, Acute Respiratory Distress Syndrome (ARDS), Lung Disease, acute respiratory distress syndrome, ards
Treatment Follow up calls
Clinical Study IdentifierNCT04619368
SponsorUniversity Hospital, Toulouse
Last Modified on27 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

adult patient
hospitalized in intensive care of the CHU anesthesia-intensive care unit (Rangueil, URM, Neurosurgery)
intubated and ventilated
supported for an ARDS according to the Berlin criteria (PaO2 / FiO2 ratio <300 mmHg)
with an rt-PCR positive to SARS-CoV-2
affiliated to the french social security

Exclusion Criteria

minor patient
patient under protective measure
ARDS in the pandemic context but rt-PCR negative to SARS-CoV-2
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