Symptomatic Therapy for Patients With Huntington's Disease

  • End date
    Dec 31, 2024
  • participants needed
  • sponsor
    Second Affiliated Hospital, School of Medicine, Zhejiang University
Updated on 24 January 2022
treatment regimen


Based on the previous symptomatic treatment of Chinese HD patients, this study intends to further optimize the treatment regimen of Chinese HD patients so as to further improve the prognosis of patients.


The purpose of the study is to evaluate symptomatic treatment regimen efficacy based on different disease stages. We previously used symptomatic treatment on Chinese HD patients and most of them got improved both in the motor symptoms and life quality. So this study intends to further optimize the treatment regimen, and set a control group to further evaluate the treatment efficacy.

Condition Huntington Disease
Treatment risperidone, coenzyme Q10, Haloperidol, Idebenone, Zoloft, Haloperidol 2Mg Tab, Risperidone 1Mg Tab, Zoloft 50Mg Tablet, Deutetrabenazine Oral Tablet [Austedo], Deutetrabenazine Oral Tablet [Austedo]
Clinical Study IdentifierNCT04071639
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
Last Modified on24 January 2022


Yes No Not Sure

Inclusion Criteria

Genetic diagnosis of Huntington's disease
Symptomatic patients with Huntington's disease
Disease duration less than 5 years -

Exclusion Criteria

(1) Movement disorder due to other definite causes instead of Huntington's
disease (2) Severe Lung, kidney or liver disease (3) Neoplastic Disease
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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