Antegrade Cerebral Perfusion and Retrograde Inferior Vena Caval Perfusion for Total Aortic Arch Replacement

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  • participants needed
  • sponsor
    West China Hospital
Updated on 22 January 2021


This study is designed as a multicenter, randomized, assessor- blinded clinical trial.The primary aim of this trial is to assess whether retrograde inferior venal caval perfusion combined selective antegrade cerebral perfusion(ACP)under mild hypothermia, compared with moderate hypothermia combined with selective ACP alone, improves the outcome for the patients undergoing total aortic arch replacement.

Condition Hypothermia, Type A Aortic Dissection, circulatory arrest
Treatment Retrograde Inferior Vena Caval Perfusion, Select antegrade cerebral perfusion
Clinical Study IdentifierNCT03607786
SponsorWest China Hospital
Last Modified on22 January 2021


Yes No Not Sure

Inclusion Criteria

Patient aged 18 yr-65yr
Patient underwent total aortic arch replacement

Exclusion Criteria

Inability to understand/give informed consent
Participation in another clinical trial that interferes with the primary or secondary outcomes of this trial
Inability to obtain superior and inferior vena caval cannulation due to pericardium adhesion
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