The Influence of Baseline Sensitivity and Expectation on Exercise-induced Hypoalgesia in Young Healthy Adults

  • End date
    Dec 30, 2022
  • participants needed
  • sponsor
    Marquette University
Updated on 22 January 2021


The purpose of this study is to investigate the influence of baseline experimental pain sensitivity and expectation on the pain response following a single exercise session. Pain assessment will be done with different intensities of noxious stimuli. In addition, the expectation of how exercise impacts pain will be studied.


The relation between baseline pain sensitivity and the pain response following exercise is not clear. The aims of this study are to investigate the influence of baseline experimental pain sensitivity on the pain response following submaximal isometric exercise, and whether expectations would influence outcomes with subsequent exposure to exercise.

Condition Diet and Nutrition, Chronic Diarrhea, Skin Wounds, Chronic Shoulder Pain, Vaginal Atrophy, Adverse Effects, Drugs, Injection Port, Breast Cancer - HER2 Positive, Anal Dysplasia, Primary Immunodeficiency, Pediatric Health, Near-Sighted Corrective Surgery, Peripheral Arterial Occlusive Disease, Healthy Subjects, Brain Function, Recurrent Respiratory Papillomatosis, Razor Bumps (Pseudofolliculitis Barbae), Metastatic Triple-Negative Breast Cancer
Treatment Submaximal isometric exercise
Clinical Study IdentifierNCT03871504
SponsorMarquette University
Last Modified on22 January 2021


Yes No Not Sure

Inclusion Criteria

Healthy adults
English proficiency

Exclusion Criteria

Acute pain condition
Chronic pain condition
Mental health disorder
Cardiovascular disease
Any chronic illness
Difficulty with physical exercise
Recent surgery
Pulmonary disease
Raynaud disease
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