Who Will Benefit From Bariatric Surgery for Diabetes?

  • End date
    Jun 5, 2028
  • participants needed
  • sponsor
    Imperial College London
Updated on 4 October 2022


A study investigating the influence of fat distribution, genetic susceptibility markers for type 2 diabetes (T2DM) and fat distribution, epigenetic and transcriptomic changes and gut hormone responses to a mixed meal on diabetes remission following bariatric surgery.

Condition NIDDM, Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2, adiposity, Obesity, Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2, type 2 diabetes mellitus, type 2 diabetes, type ii diabetes, noninsulin-dependent diabetes mellitus, diabetes type 2
Treatment Roux-en-Y Gastric Bypass (RYGB)
Clinical Study IdentifierNCT03842475
SponsorImperial College London
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Aged 18-80 years
Male or female
Body mass index 19 - 25 kg/m2
Stable weight for at least three months

Exclusion Criteria

Abnormal glucose tolerance and fasting glucose
History of any medical, or other condition, or use of any medications, including over-the-counter products, which, in the opinion of the investigators, would either interfere with the study
Without access at home to a telephone, or other factor likely to interfere with ability to participate reliably in the study
Pregnancy or breastfeeding
Unable to maintain adequate contraception for the duration of the study
Donated blood during the preceding 3 months or intention to do so before the end of the study
Current smoker
Participation in another trial within the last 3 months
Unable to understand English
Clear my responses

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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