A Phase III Randomized Multi-center Study to Determine the Efficacy of the Intercalating Combination Treatment of Chemotherapy and Gefitinib or Chemotherapy as Adjuvant Treatment in NSCLC With Common EGFR Mutations.

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    Yonsei University
Updated on 22 January 2021


This study aims to compare the efficacy of intercalating chemotherapy (gefitinib and pemetrexed/cisplatin) and chemotherapy (navelbine/cisplatin) in completely resected NSCLC with common EGFR mutations.

Condition Completely Resected NSCLC With Common EGFR Mutations
Treatment gefitinib, pemetrexed,cisplatin, Vinorelbine, cisplatin
Clinical Study IdentifierNCT03381066
SponsorYonsei University
Last Modified on22 January 2021


Yes No Not Sure

Inclusion Criteria

Completely resected non-squamous cell NSCLC with stage IIa to IIIb (excluding N3) according to Version 8 of the IASLC Staging Manual in Thoracic Oncology
Tumors with common EGFR mutations (19del or L858R)
Adequate oran function

Exclusion Criteria

Patients who were exposed to the chemotherapy or EGFR TKIs for NSCLC
Patients with interstitial lung disease
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