Pulmonary Endarterectomy Guided by CT Scanning for Patients With Chronic Thromboembolic Pulmonary Hypertension----PEACT

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  • participants needed
  • sponsor
    Sheng Liu
Updated on 22 January 2021


This study is a effectiveness study of the application of high-definition enhanced computed-tomography for patients with chronic thromboembolic pulmonary hypertension(CTEPH).The patients with CTEPH was randomized into 2 groups,precise pulmonary endarterectomy group(guided by enhanced CT scanning) and traditional pulmonary endarterectomy group,the hemodynamic changes tested with right sided heart catherization from baseline to post-operative period and end-point including peri-operative deaths,follow-up mortality,follow-up parameters of ultrasonic cardiogram(UCG),right-sided heart catherization(RHC),nuclear magnetic resonance imaging(MRI),cardiac pulmonary exercise test(CPET) are documented,so as to compare the prognosis between these 2 groups.

Condition Pulmonary Disease, Lung Disease, Pulmonary Embolism, Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension, CTEPH, Lung Disease, thromboembolic pulmonary hypertension, lung embolism
Treatment 3-D CT scanning
Clinical Study IdentifierNCT03795740
SponsorSheng Liu
Last Modified on22 January 2021


Yes No Not Sure

Inclusion Criteria

Definite diagnosed with chronic thromboembolic pulmonary hypertension with the right-sided cathrization and pulmonary angiography
The computed tomography imaging implied that the location of the embolism could be reached with surgeries

Exclusion Criteria

Beyond the age limit described above,or combined with other severe conditions such as severe organ dysfunction and considered contraindicated for surgical therapy by the cardiac surgeons
Without the consent by the patient or his/her families
Acute pulmonary embolism
Pulmonary sarcoma
Pulmonary arteritis
Combined with cardiogenic pulmonary hypertension or idiopathic pulmonary hypertension
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