Anastomotic leakage (AL) is one of the major complications after gastrointestinal surgery. Compromised tissue perfusion at the anastomosis site increases the risk of AL. Indocyanine green (ICG) combined with fluorescent near infrared imaging has proven to be a feasible and reproducible application for real-time intraoperative quantification of the tissue perfusion and cohort studies showed reduced leakage rate. Unfortunately, these studies were not randomized. Therefore, we propose a nationwide randomized controlled trial to identify the value of ICG for AL in colorectal anastomosis.
| Condition | Colorectal Cancer, Colorectal Cancer, Colon Cancer Screening, Colon cancer; rectal cancer, Inflammatory bowel disease, Inflammatory bowel disease, Crohn's Disease, Crohn's Disease, Crohn's Disease (Pediatric), Colon Cancer Screening, Colon cancer; rectal cancer, Crohn's Disease (Pediatric), Resectable Colorectal Carcinoma, crohns disease |
|---|---|
| Treatment | ICG-guided bowel perfusion assessment |
| Clinical Study Identifier | NCT04712032 |
| Sponsor | Leiden University Medical Center |
| Last Modified on | 2 February 2023 |
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