Unicompartmental Knee Arthroplasty vs High Tibial Osteotomy.

  • End date
    Oct 1, 2024
  • participants needed
  • sponsor
    Assiut University
Updated on 1 February 2021


Valgus high tibial osteotomy (HTO) and unicompartmental knee arthroplasty (UKA) are established treatment options for patients with medial compartmental osteoarthritis (OA) of the knee.However, the clinical outcomes of these treatment modalities for unicompartmental OA have become subjects of debate.


Although HTO for the correction of malalignment in the medial osteoarthritic knee has been shown to provide successful outcomes in some studies, it is technically difficult to achieve the ideal valgus position postoperatively, and the likelihood of postoperative complications after HTO is greater than that after UKA . As compared with HTO, UKA has been reported to provide better long-term results, to have a shorter time to full weight bearing, to allow easier rehabilitation, and to have fewer perioperative complications. Furthermore, indications for UKA are broadening, including younger and more active patients, since encouraging midterm and long-term results were published.

Condition Repair of knee joint, Knee Replacement, Knee Surgery, Osteoarthritis of knee, Osteoarthritis, Osteoarthritis, Knee Surgery, Gonarthrosis, Knee Replacement, knee osteoarthritis, total knee replacement, total knee arthroplasty, knee replacements, knee arthroplasty
Treatment Unicompartmental knee replacement, high tibial osteotomy
Clinical Study IdentifierNCT04467970
SponsorAssiut University
Last Modified on1 February 2021


Yes No Not Sure

Inclusion Criteria

\- Medial compartment osteoarthritis with exposed bone on both femur and tibia
-Functionally intact Anterior Cruciate Ligament (superficial damage or splitting is acceptable)
-Full thickness and good quality lateral cartilage present
-Correctable intra-articular varus deformity (suggestive of functionally intact medical cruciate ligament) 5-Medically fit showing an American Society of Anesthesiologists (ASA) of 1 or 2

Exclusion Criteria

Require revision knee replacement surgery
Have rheumatoid arthritis or other inflammatory disorders
Are unlikely to be able to perform required clinical assessment tasks
Have symptomatic foot, hip or spinal pathology
Previous knee surgery other than diagnostic arthroscopy and medial menisectomy
Previously had septic arthritis
Have significant damage to the patella-Femoral Joint especially on the lateral facet
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