Social Cognition in Patients With Amyotrophic Lateral Sclerosis

  • STATUS
    Recruiting
  • End date
    Sep 27, 2023
  • participants needed
    74
  • sponsor
    University Hospital, Angers
Updated on 27 January 2021

Summary

Amyotrophic Lateral Sclerosis, also known as Charcot disease, is a neurodegenerative disease evidenced by gradual paralysis of the muscles involved in voluntary motor function. The clinical hallmark of Amyotrophic Lateral Sclerosis is the combination of upper and lower motor neuron signs and symptoms. The most recent studies suggest that up to 50% of Amyotrophic Lateral Sclerosis patients demonstrate mild to moderate cognitive disturbance. Impaired social cognition, including a deficit in the recognition of facial emotions and the identification of vocal prosody, is recognized as a part of the cognitive phenotype of Amyotrophic Lateral Sclerosis, with crucial implications for patients' and caregivers' training. However, studies remain scarce and the data acquired must be supported. The evolution of these manifestations during the disease is still poorly understood.

In this study the investigators aim to assess the social cognition capacities of patients with Amyotrophic Lateral Sclerosis compared to healthy matched control subjects.

Details
Condition Social Cognition
Treatment neuropsychological test
Clinical Study IdentifierNCT04406675
SponsorUniversity Hospital, Angers
Last Modified on27 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patient Amyotrophic Lateral Sclerosis
Education of at least 7 years
Native language: French
Patients Amyotrophic Lateral Sclerosis
Signature of informed consent to participate in the study
Accompanied patient
Control subject
People without any pathology
Education of at least 7 years
Native language: French
Signature of informed consent to participate in the study

Exclusion Criteria

Patient Amyotrophic Lateral Sclerosis and control subject
Simultaneous participation in another interventional protocol with experimental treatment
Inability to perform cognitive study tests
Pregnant, lactating or parturient women
Persons deprived of their liberty by administrative or judicial decision
Persons under psychiatric care under duress
Persons subject to legal protection measures
Persons out of state to express their consent
People not affiliated or not beneficiaries of a social security scheme
History likely to disturb cognition
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note