Pencil Beam Proton Therapy for Pelvic Recurrences in Rectal Cancer Patients Previously Treated With Radiotherapy

  • End date
    Oct 31, 2028
  • participants needed
  • sponsor
    University of Aarhus
Updated on 27 January 2021


Study design:

A prospective phase II, non-randomized observational study of dose-escalated pencil beam proton therapy re-irradiation for pelvic recurrences from rectal cancer.

Re-irradiation is either a part of neo-adjuvant treatment or as a definitive treatment strategy for un-resectable recurrences.

Condition Recurrent Rectal Cancer, Rectal Cancer Recurrent
Treatment Pencil beam proton radiotherapy
Clinical Study IdentifierNCT04695782
SponsorUniversity of Aarhus
Last Modified on27 January 2021


Yes No Not Sure

Inclusion Criteria

Locally recurrent rectal cancer
Bioptically verified (adenocarcinoma )
Available dose plan from primary radiotherapy
Previous pelvic RT (>30Gy EQD2)
Evaluated in MDT-conferences (Herlev, Aarhus)
Age>18 years
PS 0-2
Adequate organ function
Informed consent

Exclusion Criteria

Non-resectable distant metastases (PET-CT)
Unable to undergo MRI, PET-CT
Inability to attend full course radiotherapy and follow up in the out patient clinic
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note