Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury
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- STATUS
- Recruiting
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- End date
- Dec 26, 2025
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- participants needed
- 60
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- sponsor
- Yonsei University
Summary
The purpose of our study is to determine the safety and efficacy of the combination of erythropoietin (EPO) and granulocyte-colony stimulating factors (G-CSF) in patients with neurological diseases. To be specific, our clinical study is expected that the combination injection of EPO and G-CSF shows neurotrophic and neuroprotective effects by facilitating endogenous repair process in patients with neurological diseases including stroke, cerebral palsy, or atypical parkinsonism. Therefore, we will apply our original treatment technique in patients with neurological diseases, which is expected to overcome current ethical and technical limitations of less evidenced functional recovery, hematological changes, and side effects. Eventually, We will establish a comprehensive clinical background about neurotrophic and neuroprotective effects of this hematopoietic growth factors therapy.
Details
| Condition | Cerebral Palsy, Cerebral Palsy (Pediatric), Cerebral Palsy, INTRACRANIAL HEMORRHAGE, Cerebral Palsy (Pediatric), Ischemic Stroke, Neurological Diseases, Atypical Parkinson Disease, hemorrhagic stroke, hemorrhage brain, cerebral palsy (cp) |
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| Treatment | Injection of Normal Saline, Combination injection of EPO and G-CSF |
| Clinical Study Identifier | NCT02018406 |
| Sponsor | Yonsei University |
| Last Modified on | 26 January 2021 |
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