TTHX1114(NM141) in Combination With DWEK/DSO

  • days left to enroll
  • participants needed
  • sponsor
    Trefoil Therapeutics, Inc.
Updated on 20 September 2021
Thomas M Tremblay, RN BSN
Primary Contact
Chicago Corneal Consultants (7.6 mi away) Contact
+12 other location


Open label, single-treatment, with a concurrent non-treatment control

Condition Fuchs' endothelial dystrophy, Fuchs
Treatment TTHX1114(NM141)
Clinical Study IdentifierNCT04676737
SponsorTrefoil Therapeutics, Inc.
Last Modified on20 September 2021


Yes No Not Sure

Inclusion Criteria

Fuchs Endothelial Cell Dystrophy (FECD) diagnosed more than 6 months
Scheduled for DWEK/DSO with a planned central descemetorhexis of approx 4 to 5 mm
Subjects in Group 2 must have a stable Fellow Eye with adequate function

Exclusion Criteria

Secondary corneal/ocular pathology in the Study Eye
Prior refractive surgery in the Study Eye
Prior exposure to TTHX1114
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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