Rehabilitation With Personalized Strategies According to Muscle Volume Before Knee Arthroplasty (REPERAGE)

  • End date
    Apr 29, 2024
  • participants needed
  • sponsor
    University Hospital, Brest
Updated on 29 May 2022


Preoperative rehabilitation before total knee arthroplasty (TKA) has not been proven to be effective. Latest meta-analyzes do not find any improvement of motor performance during gait 6 months after surgery. However, most of the previous studies did not specifically target muscle atrophy to design rehabilitation protocol. Pre-operative muscle atrophy, although not systematic, is often observed. The preoperative muscles volumes of thigh muscles have been poorly identified and never used to adjust the pre operative rehabilitation strategy.

As part of the "FOLLOWKNEE" (RHU) project, which attempts to implement a personalized management of TKA and its follow-up, this study wants to explore the potential effect of adapted treatment to improve muscle force and muscle volume before TKA.

Condition Gonarthrosis, Arthroplasty
Treatment Personalized rehabilitation program with electrostimulation, Global rehabilitation program
Clinical Study IdentifierNCT04318197
SponsorUniversity Hospital, Brest
Last Modified on29 May 2022


Yes No Not Sure

Inclusion Criteria

Terminal stage gonarthrosis with total knee arthroplasty (TKA) indication
TKA indicated by the surgeon
Body Mass Index < 35
Acceptance to realize a preoperative rehabilitation in outpatient setting
Adult between 18 and 80 years old
Patient affiliated to social security
Patient who signed an informed consent

Exclusion Criteria

Functionally uncomfortable osteoarticular illness (disabling pain, functional limitation of joint amplitudes or muscle strength) of controlateral leg
Unable or refusal to consent
Contraindication to electrostimulation (skin lesion, nearby implanted metallic material, implanted cardiac or neurologic electrostimulator, intolerance to muscle electrical stimulation)
Unstable medical situation preventing the continuous realization of a program of at least 4 weeks
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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