Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery

  • End date
    Dec 24, 2024
  • participants needed
  • sponsor
    The Guthrie Clinic
Updated on 24 December 2021


The purpose of this research is to compare a single shot long acting local anesthetic to catheter infusion of local anesthetic in patients undergoing video assisted thoracoscopic (VAT) surgery.


The purpose of this research is to compare Single Shot Liposomal Bupivacaine (EXPAREL®)/Bupivacaine (a long acting local anesthetic) to Ropivacaine (0.5% bolus followed by 0.2% infusion of local anesthetic using a catheter) in patients undergoing video assisted thoracoscopic (VAT) surgery.

Condition Thoracic Surgery
Treatment Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Ropivacaine (0.5% bolus followed by 0.2% infusion)
Clinical Study IdentifierNCT04559347
SponsorThe Guthrie Clinic
Last Modified on24 December 2021


Yes No Not Sure

Inclusion Criteria

Subjects who are age > 18, undergoing video thoracoscopic surgery and following Guthrie Robert Packer Hospital's Enhanced Recovery After Surgery (ERAS) protocol for Thoracic Surgery

Exclusion Criteria

weight < 50 kg, pregnant subjects
left ventricular ejection fraction < 30%
history of drug or narcotic abuse
history of allergic to amide local anesthetic
presence of contraindication for erector spinae plane block (local skin infection, sepsis, severe coagulopathy)
unable to provide consent
unable to use pain rating scales as demonstrated by verbal feedback
preoperative chronic pain on narcotics
history of renal insufficiency ( Creatinine > 1.5 mg/dl)
preoperative mild liver impairment ( i.e. AST/ALT above 1.5 times the upper normal limit)
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