The Effect of Neuropathic Pain in Patients With Combat-related Extremity Injury

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    Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Updated on 17 August 2022


It has been suggested that veterans with chronic pain might be at increased risk for the development of depression, anxiety and post-traumatic stress disorder. To date, most of the published studies have focused on chronic pain as a whole, and there are limited studies examining association of neuropathic pain with psychological comorbidity and quality of life.Combat related extremity injury significantly influences the patients' quality of life and psychological state. In this context, the purpose of this study is to illustrate to what extent neuropathic pain influences the quality of life, depression level and sleep quality of patients with combat-related extremity injury.


A total of 120 patients with combat-related extremity injury and 60 age and BMI-matched healthy controls will be participated in this cross-sectional study. The presence of neuropathic pain will be evaluated using Leeds assessment of neuropathic symptoms and signs (LANSS) questionnaire. The impact of pain on health-related quality of life will be assessed using the 36-Item Short Form Survey (SF-36). Beck Depression Scale (BDS) will be used to evaluate depression status of the patients. Quality of sleep will be assessed using the Pittsburgh Sleep Quality Index (PSQI).

Condition Peripheral Neuropathy, Peripheral Neuropathy, Neuralgia, Pain, Post-Surgical Pain, Pain (Pediatric), Pain, Post-Surgical Pain, Pain (Pediatric), neuropathic pain
Treatment The effect of neuropathic pain on quality of life, depression and sleep quality
Clinical Study IdentifierNCT04674631
SponsorGaziler Physical Medicine and Rehabilitation Education and Research Hospital
Last Modified on17 August 2022

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