Function Integrity of Neck Anatomy in Thyroid Surgery

  • End date
    Dec 12, 2026
  • participants needed
  • sponsor
    Wuhan University
Updated on 26 January 2021


Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment.

Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.

Condition Thyroid Adenoma, Thyroid Cancer, Thyroid Nodule, head and neck cancer, head and neck cancer, Thyroid disorder, Thyroid Disease, Thyroid Disorders, Thyroid Disease, Thyroid Disorders, Thyroid Cancer, thyroid carcinoma, thyroid nodules, Ablation; Retina, Ablation; Retina, Ablation; Retina
Treatment Intraoperative thermal ablation
Clinical Study IdentifierNCT04666103
SponsorWuhan University
Last Modified on26 January 2021


Yes No Not Sure

Inclusion Criteria

Patients diagnosed with unilateral thyroid carcinoma and contralateral benign nodule confirmed by preoperative ultrasound-guided fine-needle aspiration cytology
Patients with contralateral nodules 20mm and located in the thyroid gland
Patients with clinical node-negative cervical compartment at palpation and neck ultrasound

Exclusion Criteria

Previous history of neck surgery
Previous history of neck radiation therapy
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