Genetic Testing and Motivational Counseling for FH
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- STATUS
- Recruiting
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- End date
- Oct 31, 2022
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- participants needed
- 180
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- sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Summary
To date, there are highly effective lipid-lowering drugs, the combination of which makes it possible to achieve the target level of LDL-C in most patients with familial hypercholesterolemia (FH). However, the effectiveness of treatment of FH patients strongly depends on adherence to lipid-lowering therapy and to the healthy lifestyle, as well as the detection of the disease and the therapy prescription as early as possible, better in childhood. The aim of the study is to assess the impact of genetic testing and motivational counseling on the effectiveness of treatment and cascade screening in patients with FH.
Description
There are several tasks of the study:
- To assess the effect of knowledge of patients with FH about the result of their FH genetic testing on the adherence to a healthy lifestyle and hypolipidemic therapy.
- To assess the impact of knowledge of patients with FH about the result of their FH genetic testing on the effectiveness of cascade screening.
- To assess the influence of motivational counseling of patients with FH on the adherence to a healthy lifestyle and hypolipidemic therapy.
- To assess the impact of motivational counseling of patients with FH on the effectiveness of cascade screening.
Details
| Condition | genetic test, Psychological Counseling, Broad Beta Disease, genetic analysis, Hypercholesterolemia, Familial, 3, Compliance, Hypercholesterolemia, Familial, Due to Ligand-Defective Apolipoprotein B, Familial Hypercholesterolemia, Hypercholesterolemia Familial Due to Genetic Defect of Apolipoprotein B, Cascade Screening, Hypercholesterolemia, Familial, 1, Therapeutic Adherence and Compliance, Noncompliance with medication regimen, motivational enhancement therapy, Familial Hypercholesterolemia - Heterozygous, Hypercholesterolemia, Familial, 4, Autosomal Recessive, Treatment Adherence and Compliance, Familial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation, genetic tests, Hypercholesterolemia, Familial, 4, Treatment Adherence, Patient Compliance, Therapeutic Adherence, FAMILIAL HYPERCHOLESTEROLEMIA, Hypercholesterolemia, Autosomal Dominant, 3, Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B, Fredrickson Type III Hyperlipoproteinemia, Hypercholesterolemia, Familial, 2, Motivational Interviewing, Adherence, Genetic Testing |
|---|---|
| Treatment | genetic testing, Motivational Counseling, Visit 1, Visit 2, Lipid analysis, Consultation with a cardiologist-lipidologist (correction of therapy, lifestyle, diet), Visit 3 |
| Clinical Study Identifier | NCT04656028 |
| Sponsor | National Medical Research Center for Therapy and Preventive Medicine |
| Last Modified on | 1 November 2021 |
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