RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy (RESPIRE)

  • End date
    Oct 8, 2023
  • participants needed
  • sponsor
    Fondation Ophtalmologique Adolphe de Rothschild
Updated on 8 August 2022


When patients arrive in the waiting room of the MRI department, patients and holders of parental authority will be given the information note explaining the objective of the study and its unfolding. During the consultation, the radiologist will check the inclusion and non-inclusion criteria, and will take the time to answer all of their questions about the study. If the patient and the holders of parental authority agree to participate in the research, the investigative doctor will obtain his consent.

The MRI examination will be performed on a 3T multi-parametric MRI. Compared to the standard protocol, patients will benefit from an additional sequence of f-mRI, called resting state, and performed before injection of gadolinium contrast agent.

Condition Epilepsy
Treatment séquence resting state
Clinical Study IdentifierNCT04451278
SponsorFondation Ophtalmologique Adolphe de Rothschild
Last Modified on8 August 2022


Yes No Not Sure

Inclusion Criteria

Patient between 6 and 18 years old
Benefiting from an MRI as part of a preoperative assessment of lesion epilepsy
Affiliate or beneficiary of a social security scheme
Whose holders of parental authority have received informed information about the study and have given their express consent to participate in the study

Exclusion Criteria

Contraindication to absolute or relative MRI (in particular, pregnant or breastfeeding women)
History of intracranial surgery
MRI performed under general anesthesia
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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