A Study of ZN-c3 in Patients With Platinum-Resistant Ovarian Cancer

  • STATUS
    Recruiting
  • End date
    Jan 1, 2023
  • participants needed
    100
  • sponsor
    K-Group Beta
Updated on 4 May 2021

Summary

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and pharmacodynamics of ZN-c3 in combination with other drugs.

Description

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and pharmacodynamics of ZN-c3. This study consists of 2 cohorts in participants with platinum-resistant ovarian, peritoneal, or fallopian tube cancer. One cohort will test a combination of ZN-c3 and pegylated liposomal doxorubicin (PLD), and the other cohort will test a combination of ZN-c3 and carboplatin.

Details
Condition Fallopian Tube Cancer, Peritoneal Cancer, Solid Tumors, Solid Tumor, Ovarian Epithelial Cancer, Solid Neoplasm, Epithelial Ovarian Cancer, Primary Peritoneal Cavity Cancer, Epithelial Ovarian Carcinoma, Solid Tumour, ovarian epithelial carcinoma, carcinoma of the ovary, fallopian tube cancers
Treatment carboplatin, Pegylated Liposomal Doxorubicin, ZN-c3
Clinical Study IdentifierNCT04516447
SponsorK-Group Beta
Last Modified on4 May 2021

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