Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma

  • STATUS
    Recruiting
  • End date
    Dec 1, 2026
  • participants needed
    100
  • sponsor
    Helsinki University Central Hospital
Updated on 27 January 2021

Summary

The purpose of this study is to assess whether endoscopic cyclophotocoagulation added to cataract surgery lowers intraocular pressure more than cataract surgery alone in patients with normal tension glaucoma.

Description

Subjects with normal tension glaucoma that is stable with current medication needing cataract surgery are recruited in the study. All patients meeting the inclusion criteria and giving informed consent will be randomized to whether having endoscopic cyclophotocoagulation performed in the same session with cataract surgery, or cataract surgery alone.

Details
Condition Low Tension Glaucoma, Cataract, Cataracts, Glaucoma, Glaucoma, Cataracts, normal tension glaucoma
Treatment Phaco, Phaco+ECP
Clinical Study IdentifierNCT04651530
SponsorHelsinki University Central Hospital
Last Modified on27 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Signed Informed Consent
Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle
Glaucoma stable with current medication assessed by a glaucoma specialist
Clinically significant cataract

Exclusion Criteria

Secondary Glaucoma e.g. due to previous injury or uveitis
Exfoliation syndrome
Pigment dispersion syndrome
Previous transscleral or endoscopic cyclophotocoagulation
Previous other glaucoma surgery
Cataract due to eye injury or congenital cataract
Zonular weakness due to Marfan syndrome or other
Previous retinal detachment
Previous intraocular surgery like vitrectomy and other retinal surgery
Wet age-related macular degeneration
Diabetic retonopathy
Previous corneal transplant or previous refractive surgery
Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars
The patient does not want to participate in the study
The glaucoma progresses on current IOP
The patient does not speak Finnish, Swedish or English
Dementia
Only eye with vision worse than 20/200 or loss of central visual field
Clear my responses

How to participate?

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What happens next?
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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