Preoperative i.v. Iron Substitution in Patients With Colon Cancer

  • End date
    Dec 31, 2024
  • participants needed
  • sponsor
    Helsinki University Central Hospital
Updated on 26 January 2021


About 70% of colon cancer patients are anemic. Preoperative anemia in patients with colorectal cancer is associated with both impaired disease-free survival and overall survival. The purpose of this study is to compare the effects of preoperative iv iron substitution on postoperative recovery in preoperatively anemic (male Hb <130, female Hb <120) and iron deficient colon cancer patients in a prospective setup. As a primary outcome, the effect of iv-iron substitution on postoperative complications is investigated.


Randomized preoperative iron substitution for patient with iron deficient anemia

Condition Colorectal Cancer, Colorectal Cancer, Colon Cancer Screening, Colon cancer; rectal cancer, Malignant neoplasm of colon, Colon Cancer, Colon Cancer Screening, Colon cancer; rectal cancer, Colon Cancer, colon carcinoma
Treatment Ferric carboxymaltose
Clinical Study IdentifierNCT04653181
SponsorHelsinki University Central Hospital
Last Modified on26 January 2021


Yes No Not Sure

Inclusion Criteria

Age> 18 years
Dg: Colon ca
The planned measure: the colon resection
Men: Hb <130, women: Hb <120 and iron deficiency (elevated TfR, low TrFesat or low ferritin)

Exclusion Criteria

hyperreactivity for Ferinject
refusal for participation
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