Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

  • STATUS
    Recruiting
  • End date
    Dec 20, 2023
  • participants needed
    31
  • sponsor
    Memorial Sloan Kettering Cancer Center
Updated on 23 May 2022
remission
fludarabine
mycophenolate mofetil
lymphoma
myelofibrosis
busulfan
cyclosporine
myeloproliferative disorder
myelodysplasia
flow cytometry
ejection fraction
growth factor
cell transplantation
leukemia
hematologic disorder
minimal residual disease
cytopenia
residual tumor
clofarabine
consolidation chemotherapies
blast cells
hla typing

Summary

This is a single-arm study to investigate 1-year treatment related mortality (TRM) in patients with life threatening non-malignant and malignant hematologic disorders who do not have a matched related donor for allogeneic transplantation.

Details
Condition AML, ALL, MDS, MPD Withou Myelofibrosis, NHL or HL, Inherited Metabolic Disorders, Hemoglobinopathies, Bone Marrow Failure, HLH
Treatment mycophenolate mofetil, busulfan, Fludarabine, Clofarabine, Cyclosporine-A, Cord Blood Graft
Clinical Study IdentifierNCT04644016
SponsorMemorial Sloan Kettering Cancer Center
Last Modified on23 May 2022

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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