Opioid Free Anesthesia in Breast Cancer Surgery

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    Peking University People's Hospital
Updated on 18 April 2022


A comparison of incidences of postoperative nausea and vomiting (PONV) , postoperative pain severity and recovery parameters in breast cancer patients receiving opioid or opioid-free general anesthesia.


Breast cancer is one of the most common oncologic diagnosis in women. Surgery is traditionally performed under general anesthesia with opioid-based analgesia. It is associated with higher incidences of PONV, more severe acute postoperative pain and increased incidences of chronic pain. The possibility of higher risk of metastasis has also been reported.

The purpose of our study is to compare the opioid-free general anesthesia with the opioid-based general anesthesia with respect to the quality of recovery, postoperative pain and cancer recurrence and metastasis.

Condition Opioid Free Anesthesia
Treatment Sham block, paravertebral block, opioid free anesthesia, opioid general anesthesia
Clinical Study IdentifierNCT04390698
SponsorPeking University People's Hospital
Last Modified on18 April 2022

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