Translating the ABCS Into HIV Care

  • End date
    Jul 27, 2022
  • participants needed
  • sponsor
    University of Rochester
Updated on 27 January 2021


The overall objective of this project is to develop and rigorously test implementation strategies to address the gap in scientific knowledge of lower use of evidence-based interventions commonly referred to as the ABCS (aspirin, blood pressure control, cholesterol control, and smoking cessation)which contributes to the growing CVD morbidity and mortality among PLH.


Our project has two major aims:

Aim 1: To assess the impact of the implementation of an evidence-based, multilevel strategy to reduce cardiovascular vascular disease (CVD) among PLH.

Aim 2: To assess the process of implementation of these strategies using RE-AIM QuEST. Using both quantitative and qualitative methods, we evaluate the process of implementation by assessing Reach, [Effectiveness addressed in Aim 1], Adoption, Implementation and Maintenance whilst integrating Qualitative Evaluation for Systematic Translation.

Condition HIV, HIV positive, HIV infection, AIDS Vaccines, Cardiovascular Risk Factor, HIV (Pediatric), HIV Infections, human immunodeficiency virus, hiv disease, HIV Vaccine, hiv vaccines
Treatment ABCS training
Clinical Study IdentifierNCT03902431
SponsorUniversity of Rochester
Last Modified on27 January 2021


Yes No Not Sure

Inclusion Criteria

Serve a cohort of at least 100 HIV patients
Have an Electronic Health Record (EHR)
Agree to collaborate on implementing feasible adaptations of intervention strategies
Patient of the site with a diagnosis of HIV
Age 40-79 years
% risk for CVD as calculated using the ASCVD Risk Estimator Plus
Willing to participate
No plans to leave the site in the next 12 months
Proficient in either English or Spanish
Own a cell phone with texting capabilities
Physicians, Physicians Assistants, or Nurse Practitioners who provide direct HIV care to patients
Work at a participating site
Willing to implement the project's intervention strategies

Exclusion Criteria

Currently participating in another CVD trial
Have experienced a prior cardiac or vascular event such as myocardial infarction (MI) or cerebrovascular accident (CVA)
Have had a CVD procedure such as installation of a stent or angioplasty
Have peripheral vascular disease, intermittent claudication or peripheral arterial disease
Are pregnant
Lacks capacity to consent
Planning to leave the site within the next 12 months
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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