Inhaled Heparin for Hospitalised COVID-19 Patients

  • participants needed
  • sponsor
    Australian National University
Updated on 5 December 2021


This meta-trial is a prospective collaborative individual participant data meta-analysis of randomised controlled trials and early phase studies. Individual studies will be conducted in multiple countries, including Australia, the UK, the USA, Ireland, Argentina, Brazil and Egypt.

Adult patients admitted to the hospital with confirmed SARS-CoV-2 infection, who do not require immediate mechanical ventilation, will be randomised to inhaled nebulised heparin or standard care for up to 21 days or until the patient has no respiratory symptoms. All studies will collect a minimum core dataset. The primary outcome for the meta-trial is the proportion of patients who receive invasive mechanical ventilation censored at day 28. Individual studies may have specific outcome measures in addition to the core set.

Condition COVID19
Treatment Unfractionated heparin
Clinical Study IdentifierNCT04635241
SponsorAustralian National University
Last Modified on5 December 2021

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