Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

  • STATUS
    Not Recruiting
  • End date
    Mar 15, 2023
  • participants needed
    200
  • sponsor
    AstraZeneca
Updated on 2 June 2022
hysterectomy
follicle stimulating hormone
topical agents

Summary

The purpose of the study is to compare the efficacy and safety of benralizumab versus placebo and to compare benralizumab dosing regimens during extension period.

Description

The aim of this study is to investigate the use of benralizumab as treatment for patients with moderate to severe atopic dermatitis (AD) who remain symptomatic despite treatment with topical medications. It is proposed that benralizumab will deplete eosinophils from affected skin, improve symptoms of AD, and improve AD-related quality of life. This Phase 2 study is designed to compare the efficacy of treatment with benralizumab versus placebo and compare benralizumab maintenance dosing regimens in the extension period.

Details
Condition Dermatitis, Dermatite Atopique, Atopic Dermatitis, Eczema (Atopic Dermatitis), ATOPIC DERMATITIS, Dermatitis, Atopic, Eczema (Atopic Dermatitis - Pediatric), Hand Dermatitis, Eczéma (Dermatite Atopique), Eczema
Treatment benralizumab, Placebo / Benralizumab
Clinical Study IdentifierNCT04605094
SponsorAstraZeneca
Last Modified on2 June 2022

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