Auditory-motor Coupling in Multiple Sclerosis With Cerebellar Lesions

  • End date
    Dec 31, 2022
  • participants needed
  • sponsor
    Hasselt University
Updated on 26 January 2021


This study is a case-control observational study, involving persons with multiple sclerosis and healthy controls. The study contains 1 descriptive and 4 experimental sessions. In the descriptive session, participant's clinical motor and cognitive functions are collected. In the first experimental session, participant's beat perception and synchronisation abilities is examined within a finger tapping paradigm. In the following experimental sessions participants synchronsiation abilities is examined during walking paradigms, to music and metronomes, at different tempi and alignment strategies. In the latter three sessions, apart from outcome measures of synchronization the following will be collected as well: spatio-temporal gait parameters, perceived fatigue, perceived motivation and perceived speed of walking.

Condition Multiple Sclerosis, Brain Lesions, Brain Lesion, Cerebral Lesion, Radiologically Isolated Syndrome, Dermatite Atopique modérée ou grave, multiple sclerosis (ms)
Treatment motor entrainment to auditory cues and music during walking on quality of movement
Clinical Study IdentifierNCT04639401
SponsorHasselt University
Last Modified on26 January 2021


Yes No Not Sure

Inclusion Criteria

diagnosis of Multiple sclerosis >1 year
type of lesions: cerebellar lesions
walking speed 0.8-1.2m/s, ability to walk for 6 minutes continuously (canes and rollators are permitted)

Exclusion Criteria

relapse 3 months prior to enrollment
cognitive impairment impeding understanding of instructions
beat amusia
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