Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients

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  • participants needed
  • sponsor
    Jannie Bisgaard Stæhr
Updated on 29 November 2020


To investigate the effect of intercostal blockade with and without adjuvants.


Video-assisted thoracoscopic surgery (VATS) is a minimally invasive routine procedure. It's less invasive than thoracotomy but postoperative pain is still a problem.

At Aalborg University Hospital, intercostal blockades with bupivacaine is used as standard pain treatment for patients undergoing VATS. Adding adjuvants to the blockades may prolong the effect.

The aim of this study is to investigate if intercostal nerve blockade with adjuvants (dexamethasone and adrenaline) will result in better pain management.

Treatment Dexamethasone, Bupivacain, Bupivacaine with Adrenaline
Clinical Study IdentifierNCT04633850
SponsorJannie Bisgaard Stæhr
Last Modified on29 November 2020

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Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Gender: Male or Female
Do you have any of these conditions: carcinoma lung or thoracoscopic surgery or nerve blocks or Postoperative pain or video-assisted thoracic surgery or local anesthetic or nerve blockade...?
Do you have any of these conditions: Nerve Block or thoracoscopic surgery or video-assisted thoracic surgery or Local anesthesia or Postoperative pain or carcinoma lung or local anestheti...?
Consecutive adult patients over 18 years of age scheduled to undergo VATS
because of verified/suspected lung cancer

Exclusion Criteria

Inability to understand verbal and written information
Preexisting chronic pain condition
Preoperative daily treatment with pain medication (Non-opioids, opioids, gabapentin/pregabalin)
Previous thoracic surgery
Previous chemotherapy due to thoracic malignancy and / or radiation therapy. to the thorax
Pregnant women
Autoimmune neuromuscular diseases (sclerosis, peripheral neuromuscular disorders). General muscle weakness or atrophy
Hypersensitivity, allergy or intolerance to dexamethasone, bupivacaine or adrenaline
Preoperative epidural anaesthesia
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