Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC) (PiSCATIN)
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- STATUS
- Recruiting
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- End date
- May 15, 2027
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- participants needed
- 700
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- sponsor
- Annika Bergquist
Summary
This is a randomized, double-blind, placebo controlled multicenter study.
A total of 700 patients will be included.
The study will include patients with primary sclerosing cholangitis (PSC) for daily intake of 40 mg simvastatin/placebo for 5 years. The aim is to study effect of prognosis of PSC by long term intake of simvastatin. Outcome measures are death, liver transplantation, cholangiocarcinoma or bleeding from esophageal varices.
Subjects will be randomized (1:1) between Simvastatin and placebo.
Details
| Condition | Primary Sclerosing Cholangitis |
|---|---|
| Treatment | simvastatin 40mg, Placebo Oral Tablet |
| Clinical Study Identifier | NCT04133792 |
| Sponsor | Annika Bergquist |
| Last Modified on | 6 May 2022 |
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