Efficacy and Safety of JMT103 in Patients With Bone Metastases From Solid Tumors

  • STATUS
    Recruiting
  • participants needed
    150
  • sponsor
    Shanghai JMT-Bio Inc.
Updated on 29 June 2022

Summary

This is a randomized, open-label, dose-finding, multi-centre, phase b study to evaluate the efficacy and safety of JMT103 in patients with bone metastases from solid tumors.

Description

The objective of this trial is to evaluate the efficacy and safety of JMT103 in patients with bone metastases from solid tumors.

Eligible patients will be randomly assigned to receive JMT103 120mg subcutaneously (SC) every 4 weeks (Q4W), 120mg subcutaneously (SC) every 8 weeks (Q8W) and 180mg subcutaneously (SC) every 8 weeks (Q8W) in a 1:1:1 ratio. Patients will receive the treatment until the completion of 48 weeks of treatment, intolerable toxicity, loss to follow-up, withdrawal (patient's decision or investigator's decision), whichever comes first.

Details
Condition Bone Metastases From Solid Tumors
Treatment Drug: JMT103- 120 mg SC Q4W, Drug: JMT103- 120 mg SC Q8W, Drug: JMT103- 180 mg SC Q8W, Dietary Supplement: Calcium Dietary Supplement: Vitamin D
Clinical Study IdentifierNCT04630522
SponsorShanghai JMT-Bio Inc.
Last Modified on29 June 2022

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