LOAD VS Levofloxacine Concomitant

  • End date
    May 30, 2024
  • participants needed
  • sponsor
    Damascus Hospital
Updated on 26 January 2021


Comparison Efficacy of two weeks Therapy with Doxycycline,levofloxacine,Tinadizole Versus Levofloxacine,Tinadizole,Amocillin on Eradication of Helicobacter Pylori in Syrian population.

Condition Helicobacter Pylori Infection, H. Pylori Infection
Treatment doxycycline, Levofloxacin 500mg
Clinical Study IdentifierNCT04626193
SponsorDamascus Hospital
Last Modified on26 January 2021


Yes No Not Sure

Inclusion Criteria

Patients are aged greater than 18 years old who have H. pylori infection diagnosed by any of following three methods
Positive rapid urease test (CLOtest)
Histologic evidence of H. pylori by modified Giemsa staining
Positive 13C-urea breath test. without prior eradication therapy and are willing to receive therapy

Exclusion Criteria

Children and teenagers aged less than 18 years
Previous eradication treatment for H. pylori
Patients who took any drug, which could influence the study results such as proton pump inhibitor, H2 blocker, mucosal protective agent and antibiotics
History of gastrectomy
Gastric malignancy, including adenocarcinoma and lymphoma
Previous allergic reaction to antibiotics (Amoxicillin, Tinadizole
Doxycycline,Bismuth subsalicylate,) and prompt pump inhibitors (Es- omeprazole)
Contraindication to treatment drugs
Pregnant or lactating women
Severe concurrent disease
Liver cirrhosis
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