Effect of Use of DryNites Absorbent Pants on the Rate of Spontaneous Resolution of Paediatric Nocturnal Enuresis (NE)

  • days left to enroll
  • participants needed
  • sponsor
    Kimberly-Clark Corporation
Updated on 26 April 2022
nocturnal enuresis
Accepts healthy volunteers


Children vary in the age at which they achieve night-time dryness; in almost all cases children will stop bed-wetting without any need for treatment. Use of absorbent pants for the management of nocturnal enuresis is controversial regarding the impact on the speed at which children become dry throughout the night. The aim of this study is to determine the effect of using DryNites absorbent pants in children with monosymptomatic nocturnal enuresis on the speed they become dry throughout the night compared with removing absorbent pants.

Condition Nocturnal Enuresis
Treatment DryNites Pyjama Pants
Clinical Study IdentifierNCT04620356
SponsorKimberly-Clark Corporation
Last Modified on26 April 2022


Yes No Not Sure

Inclusion Criteria

Patient aged between 4-8 years at the time of enrollment
Have a clinical diagnosis of monosymptomatic primary NE
Have been dry in the day for >/= 6 months prior to enrollment
Have on average no more than 1 dry night per month during the past 6 months at enrollment
Have an informed consent signed by the their parent(s)/carer(s)

Exclusion Criteria

Children in foster/court care
Have implemented any previous intervention to address NE (use of prescribed alarm schedule, desmopressin, imipramine, anticholinergics) or withdrawal of pants/nappies for > 7 days in the previous 6 months
Have secondary NE
Have wetting in the day
Have faecal soiling
Have known urinary tract disease
Have diabetes
Receive any regular intake of medication
Have a known developmental/neurological disorder
Have links to Kimberly-Clark of any kind (including family relations employed by Kimberly-Clark, holding stocks or share in Kimberly-Clark)
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